"Osteosarcoma (Bone Cancer)
A multi-breed case-control study of the risk factors for osteosarcoma found that spay/neutered dogs (males
or females) had twice the risk of developing osteosarcoma as did intact dogs13.
This risk was further studied in Rottweilers, a breed with a relatively high risk of osteosarcoma. This
retrospective cohort study broke the risk down by age at spay/neuter, and found that the elevated risk of
osteosarcoma is associated with spay/neuter of young dogs14. Rottweilers spayed/neutered before one
year of age were 3.8 (males) or 3.1 (females) times more likely to develop osteosarcoma than intact dogs.
Indeed, the combination of breed risk and early spay/neuter meant that Rottweilers spayed/neutered before
one year of age had a 28.4% (males) and 25.1% (females) risk of developing osteosarcoma. These results
are consistent with the earlier multi-breed study13 but have an advantage of assessing risk as a function of
age at neuter. A logical conclusion derived from combining the findings of these two studies is that
spay/neuter of dogs before 1 year of age is associated with a significantly increased risk of osteosarcoma.
The researchers suggest a cause-and-effect relationship, as sex hormones are known to influence the
maintenance of skeletal structure and mass, and also because their findings showed an inverse relationship
between time of exposure to sex hormones and risk of osteosarcoma.14
Page 5 of 12
The risk of osteosarcoma increases with increasing breed size and especially height13. It is a common
cause of death in medium/large, large, and giant breeds. Osteosarcoma is the third most common cause of
death in Golden Retrievers10 and is even more common in larger breeds13.
Given the poor prognosis of osteosarcoma and its frequency in many breeds, spay/neuter of immature dogs
in the medium/large, large, and giant breeds is apparently associated with a significant and elevated risk of
death due to osteosarcoma."
Z
http://www.naiaonline.org/pdfs/LongTerm ... InDogs.pdfZ tego wynika, ze ryzyko osteosarkomy zwieksza zwlaszcza kastracja we wczesnym wieku. Oraz predyspozycje rasowe i wielkosc docelowa psow.
I bardzo ciekawy artykul z argumanetami za i przeciw
http://www.psy.pl/archiwum-miesiecznika/art2021.htmlI jeszcze o kastracji, wieku,w ktorym ja wykonanoi osteosarkomie
http://cebp.aacrjournals.org/content/11 ... 4.full?eaf